Left looks like SecondLife.
Belleza Freya Mesh body in the gals.
Probable VRChat, but it could just as easily be a custom Unity app.
I wouldn't be surprised if they're using Lighthouse, HTV Vive, Valve Knuckles controllers, possibly 3 Vive Trackers to get tracking for torso and feet.
Lots of people already do character mods for VRChat in Unity.
They're not the first to use it. There actually a few models who have been mixing it into their shows for the last year.
Also doing hybrid shows, Like putting their VRChat avatar into their bedroom. Or putting themselves into VRChat. Selling access to their show in VRChat.
Vive is like 399.00
Nuckles is like 279.00
3 trackers 300.00
A compute that can handle it is probable handle VR and streaming probable at least 1,000.